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This gene encodes a transcription element that belongs to your homeobox gene family. Genes of this family members are hugely conserved between vertebrates and important for vertebrate embryonic development. This gene is implicated in fetal skin advancement and cutaneous regeneration.

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In mice, an analogous gene was demonstrated to exhibit temporal and spatial colinearity in the key physique axis from the embryo, but wasn't expressed while in the secondary axes, which indicates capabilities in overall body patterning alongside the axis. This gene and various HOXB genes sort Continue a gene cluster on chromosome 17 in the 17q21-22 area.[6]

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